

Immediate and long-lasting wrinkle correction
The answer to long-lasting wrinkle correction is Restylane.®1
Before choosing a wrinkle correction treatment, there are a few things you
should know.
Before Treatment After Treatment
Q What is Restylane®?
A Restylane is a safe and natural cosmetic dermal filler that restores volume
and fullness to the skin to correct moderate to severe facial
wrinkles and folds, such as nasolabial folds.
Q What is Restylane made of?
A Restylane is the first cosmetic dermal filler made of non-animal-based
hyaluronic acid. Hyaluronic acid is a natural substance that
already exists in the human body and is used to provide volume and fullness
to the skin. The hyaluronic acid in Restylane is a crystal-clear gel called
NASHA,™ or Non-Animal Stabilized Hyaluronic Acid. NASHA is biodegradable
and fully biocompatible with human hyaluronic acid.
Q How is Restylane different than other hyaluronic acid-based products?
A Unlike rooster-derived hyaluronic acidbased products, Restylane is free
from animal proteins. This quality limits any risk of animal-based disease
transmission or allergic reaction. Restylane contains trace amounts of
gram-positive bacterial proteins and should not be used by patients with a
history of allergies to such material. Additionally, Restylane has the highest
concentration of hyaluronic acid available in a dermal filler.
Before Treatment After Treatment
Q Is Restylane® safe?
A Yes. Restylane has been used by dermatologists and plastic surgeons
since 1996 worldwide. There is limited risk of animalbased disease
transmission or allergic reaction. Restylane is fully biocompatible
and allergy testing is not required. Restylane contains trace amounts of gram-
positive bacterial proteins and should not be used by patients with a history of
allergies to such material. After your treatment, you might have some redness
or swelling. This will normally last less than seven days. Sunbathing and cold
outdoor activities should be avoided until any redness or swelling disappear. If
you are pregnant, breastfeeding, or under 18, you shouldn’t use Restylane.
Q Can Restylane be used anywhere on the face?
A Restylane has been used in more than 1.5 million treatments in over 60
countries to correct a variety of wrinkles. In the U.S. the FDA has approved
Restylane for wrinkles and folds like the ones from the nose to the corners of
the mouth. Your doctor will consult with you prior to your injection regarding
common treatment areas.
Q How long does Restylane last?
A Restylane is proven to deliver long-lasting results. Studies have shown that
Restylane effects generally last for about six months1. Restylane’s
stabilization technology helps maintain the cosmetic effect until the injected
material is nearly gone. Nasolabial folds before treatment Restylane® is
indicated for the treatment of moderate to severe facial wrinkles and folds
After treatment with three Restylane® 0.7 mL syringes Individual results may
vary.
Before Treatment After Treatment
Q How often should I have Restylane® treatments done?
A Treatments are typically scheduled twice a year. Having a touch-up
treatment before the product has fully dissipated may enhance the lasting
effect.
Q What should patients do prior to treatment?
A Restylane requires no pretesting, but you should take a few precautions
before being treated. Avoid using aspirin, non-steroidal anti-inflammatory
medications, St. John’s Wort, or high doses of Vitamin E supplements
prior to treatment, because these may increase bruising or bleeding at the
injection site. Also, if you have previously suffered from facial cold sores,
discuss this with your physician. He/She may consider prescribing a
medication to minimize recurrence.
Q How is Restylane different from Botox® Cosmetic?
A Restylane is a natural, cosmetic filler. In contrast, Botox Cosmetic is a drug
that blocks nerve transmission and relaxes the underlying muscles. Many
patients have been very pleased after receiving treatment with both products.
Q How is Restylane different from bovine collagen?
A Bovine collagen is derived from animals (cows) and requires an allergy test.
Restylane can be administered immediately—no waiting is required.
Before Treatment After Treatment
Before Treatment After Treatment
Before Treatment After Treatment
